Spontaneous AE reporting will be entered in REDCap Cloud by the subject during subject follow-ups, using the Subject AE log. Physicians will verify and assess all AEs entered at physician follow-ups, using the Physician AEs form. All serious adverse events will be sent directly to Canopy Growth’s Global Pharmacovigilance Department (GPVD) in real-time, where they will be reviewed with respect to country specific regulatory requirements. All non-serious adverse events will be sent in a monthly report to GPVD.
Together, physician and subject will complete the follow-up visit assessment measuring:
The following activities will be completed at each physician-verified follow-up visit:
• Incidence of AEs stratified by product and formulation.
Duration of Subject Participation and Treatment:
Chronic pain affects at least 10% of the global population but is often poorly managed, given the variable efficacy of available pharmacological treatments and the limited accessibility of multidisciplinary interventions. The legalization of cannabis in at least 14 countries and the increasing regulatory approval of cannabis preparations and synthetic cannabinoids and analogues have led to a growing interest in the use of medical cannabis products to manage chronic pain. This use is supported by research demonstrating important interactions between cannabinoids and the human endocannabinoid system and pain modulation pathways. While medical cannabis products are increasingly available to practitioners who treat pain, there is little evidence-based guidance for prescribing or titrating these treatments to manage chronic non-cancer pain. This prospective registry aims to assemble real-world data regarding the use of Spectrum Therapeutics (ST) medical cannabis products in subjects with chronic non-cancer pain in countries where these products are commercially available. The registry will also assess treatment outcomes, including pain and related symptoms, global impressions of improvement, and change in concomitant pain medications (opioid use in particular), to better inform the utility of ST products for chronic non-cancer pain management.
In the event of ST treatment discontinuation or study dropout, physicians will be asked to attempt to follow-up with subjects for the completion of the ST Discontinuation assessment and Exit assessment. Based on physician answers to the ST Discontinuation Assessment, subjects will either stay enrolled in the study (e.g., discontinue all cannabis treatment, but continue to be monitor by site physician for chronic pain), or be withdrawn (e.g., unwilling to stay in the study, switched cannabis licensed producer).
Educational vids? Check. Informative articles? Check. Some fun stuff to kill time with? Double-check. But what are you doing reading this totally unnecessary blurb? Get in there already.
Expert advice and simple offerings — that’s what Spectrum Therapeutics is all about.
Change Your Language
Hi. We’re Tweed, Canada’s leading source for all things cannabis. For us, it’s about more than just growing seeds into plants—it’s about starting a conversation, opening minds to fresh perspectives, and, perhaps most of all, becoming a part of the fabric of every neighbourhood that welcomes us.
Spectrum Therapeutics provides customers with a consistent offering of dried flower, oil, and softgel products — all of which have been categorized using a simple, colour-coding system.
If medical cannabis is something you’re interested in learning more about, Spectrum Therapeutics is a good place to start, as it keeps you informed with clear, accurate, and balanced information by providing links to some of the industry’s most experienced cannabis educators.
Dried cannabis is offered as either dried whole flowers (“bud”) or milled (“prepared” or “ground”). Whole flowers from the female cannabis plant are harvested, the stem and leaves are trimmed, and then the flowers are dried to a specific moisture content.
– Carefully grown, high-quality flower
– Cannabis-infused dark milk chocolate made from meticulously sourced ingredients
– The Tokyo Smoke Luma™ vape system, which combines thoughtful design and premium materials with rapid onset of effects
Concentrated cannabis resin, containing cannabinoids and other active compounds, is extracted from cannabis flowers that have undergone thermal decarboxylation, then diluted with a food-grade carrier oil to make a product for you to take orally from a syringe. This allows you to know exactly how much THC and CBD you are taking in each dose.
By building a program that gathers passionate and skilled producers together in one place, Spectrum Therapeutics is able to bring to our patients the best variety of cannabis from some of the most innovative producers in the country. It’s all about two things:
Cannabis-infused edibles are an innovative format that is suitable for those looking for an alternative method of consuming medical cannabis. Edible products contain a consistent amount of specially formulated cannabis extract that includes THC, CBD, or a combination of both.