The Epidiolex research we touched on earlier ( 2015) that was researching the effects of cannabidiol on patients with treatment-resistant epilepsy reported diarrhoea as a side effect of Epidolex, the CBD-based epilepsy drug. Of the 214 participants between the ages of 1 and 30 with severe epilepsy, 19% reportedly experienced diarrhoea. Though this may seem like a huge proportion, it is important to remember that the concentration of CBD and dosage in the study were much higher than the typical concentration found in a commercial CBD product. Participants were receiving 2-5 mg of 99% pure CBD per 1 kg of their body weight per day. Later on, their doses were increased, so they were eventually taking up to 50 mg of CBD per kg of body weight per day.
Besides cannabidiol, other parts of cannabis are also alleged to aid sleep. One of cannabis’ abundant terpenes, myrcene, seems to have soporific effects, with research testifying that myrcene can enhance muscle relaxation and increase sleep time.
Drinking plenty of water before and after consuming CBD can help avoid and potentially offset this adverse reaction.
Who should avoid CBD?
According to some studies, CBD can lower blood pressure. Those who experience hypotension, then, might need to monitor their blood pressure when trying new CBD products, and cease their intake if necessary.
While every person has unique biological makeup, the vast majority of people can ingest CBD oil without feeling any unpleasant side effects.
On a brighter note, CBD has been highlighted in research to help manage our moods and alleviate feelings of stress and anxiety. It is thought that cannabidiol can work with important mood-balancing neurochemicals in our brain to positively impact our mental state, according to studies such as those done by Blessing et al. in 2015 , De Mello Schier et al. in 2014 and Crippa et al. in 2009 . In fact, Crippa and his team asserted that CBD could have “a pharmacological profile comparable to that of mood stabilisers”. Studies on animals have reached similar conclusions about the mood-balancing effects of CBD.
Another appealing aspect of CBD use is that it is extremely well-tolerated in the body, with few side effects; it is also non-intoxicating and non-addictive – so there is no risk of becoming hooked on it, as you might with opioids. Let’s take a look at the benefits in greater detail.
CBD is an herbal remedy–a treatment that comes from a plant — in this case it is the cannabis sativa plant. Cannabis sativa has been used for thousands of years for its healing and for mind-altering effects.
CAUTION: Fatty foods may increase how CBD is absorbed by the body.
What Is CBD?
An animal study found transdermal CBD lessened the pain and inflammation of arthritis.
Studies looked at the use of cannabinoids (THC alone and CBD combined with THC) in people with chronic pain. In general, there were improvements in pain measures, but they were not statistically significant.
There are also studies of oral, topical, and inhaled CBD for use in many other conditions including: dystonia (movement disorder), Fragile X syndrome (rare genetic disorder), graft-versus-host disease (bone marrow transplant rejection), multiple sclerosis (MS), opioid withdrawal, schizophrenia, and smoking cessation. CBD is also used to alleviate Parkinson’s symptoms, but there are some studies that advise against it.