CBD’s ability to calm is perhaps its most popular effect and the reason its use is so widespread. A 2017 study in the Brazilian Journal of Psychiatry tested the anxiety levels of 57 men in a simulated public speaking test. Some received a placebo while others received either 150 milligrams, 300 milligrams or 600 milligrams of CBD before their speeches. Those who received 300 milligrams of CBD experienced significantly reduced anxiety during the test compared to those who received the placebo. Interestingly, participants who received either 150 or 600 milligrams of CBD experienced more anxiety during the test than the 300 milligrams group.
In 2018, in a study of more localized treatment, researchers administered a synthetic CBD gel in either 250-milligram or 500-milligram doses daily or a placebo to patients with knee pain due to osteoarthritis. Patients also stopped taking any other anti-inflammatory medications or painkillers, with the exception of acetaminophen, before and during the study period.
2. Treat Select Epilepsy Syndromes
Four other human trials from 2012 to 2016 suggest CBD reduces PTSD symptoms, although some include THC, or tetrahydrocannabinol, the main mind-altering element in cannabis. When THC and CBD work together, they create what’s called an “entourage effect,” complementing each other’s benefits and potency. For example, taking the same dose of THC and CBD together tempers the “high” from THC, while just a little THC paired with more CBD enhances the effects of the CBD.
In another small study, 13 patients with type 2 diabetes who weren’t on insulin treatment were given both CBD and a placebo (in lieu of insulin). Researchers found CBD decreased their levels of resistin (which causes resistance to insulin, the protein that regulates sugar levels) and increased their levels of glucose-dependent insulinotropic peptide (a hormone that ensures a sufficient release of insulin from digested food) compared to their baselines before they started the test. These results suggest CBD could be a natural treatment for diabetes by helping the body regulate insulin-related hormone levels.
Other studies find CBD helpful in reducing various psychiatric and medical symptoms like anxiety, insomnia and pain in patients with substance use disorders, indicating that CBD may be an effective treatment for opioid addiction. However, further studies are necessary.
Conclusion: CBD is beneficial for treating certain types of epilepsy.
Beneficial effects on anxiety after taking CBD were reported in an observational study where 21 patients out of 400 had anxiety. 8
More recent research points to THC being more effective at reducing nausea and vomiting than CBD.
Anxiety scores decreased in a large case series of 72 patients, with 57 patients (79.2%) reporting decreased scores within the first month after CBD treatment. 9
Other trials of 300 mg of CBD in people with anxiety or depression showed that CBD appeared to preserve sleep architecture, meaning it was unlikely to have any negative effects on sleep quality. 10
Furthermore, pain can include neuropathy or nerve damage, and studies show that CBD oil can help alleviate pain from HIV, diabetes, and other sources.
Even so, there are still many people obtaining CBD from online platforms with a medical cannabis license. With the current bipartisan consensus in Congress trying to make hemp crops legal, the legality of CBD is expected to eventually change.
6.2 Lowered Risk of Cardiovascular Disease
Summary: Effective – Academic research proves that CBD can help alzheimer’s.
Women with fibromyalgia experience migraines that also disrupt sleep as well. This disorder is the most common diagnosis  in American rheumatology practices. In Italy, the authors noted that this condition, like migraines, can be associated with secondary hyperalgesia  (a lowered threshold to pain in primarily affected areas).
Luckily, the same way CBD oil has shown tremendous results for the inside of the body; it also does the same for the skin. People have started embracing CBD oil skin products due to their ability to fight inflammations and breakouts.