CBD is often extracted from the cannabis sativa plant in oil form and mixed with an inert carrier oil like hemp seed oil for consumption. In recent years, CBD oil has skyrocketed in popularity thanks to its purported calming effects. It can now be found in a range of products from simple oil tinctures to CBD-infused potato chips.
Margaret Rajnic, a doctor of nursing practice experienced in medical cannabis and CBD, emphasizes the importance of using therapy in tandem with any type of cannabis or CBD for PTSD. “There is an amount of therapy that is needed for PTSD,” she says. “But CBD will give you that little bit of decreased anxiety.”
1. Offset Anxiety and Depression
The results were interesting, although not entirely conclusive. On one hand, those treated with CBD did not experience much change in pain when compared with placebo patients. On the other hand, there were statistically significant differences between the group receiving the 250-milligram dose and the placebo group when measuring the average weekly improvement of their worst pain levels and their WOMAC (Western Ontario and McMaster Universities Arthritis Index) physical function rating. Additionally, men seemed to benefit from CBD more significantly than women in this test.
Research suggests people with ALS can benefit from the entourage effect created by the combination of THC and CBD, similar to people with PTSD. In a 2019 study, patients received a combination of THC and CBD in varying doses depending on their needs and preferences. Those with mild, moderate or severe spasticity (muscle tightness and stiffness) due to ALS reported high levels of satisfaction with the treatment, and those with moderate to severe spasticity reported higher satisfaction rates than those with mild spasticity.
Meanwhile, continued studies in the U.S. indicate CBD is effective in treating chronic, non-cancer pain. In one 2020 study, researchers administered CBD topically to a group of patients with symptomatic peripheral neuropathy (a result of brain nerve and spinal cord nerve damage) while another group with the same condition received a placebo. Results showed a significant reduction in intense, sharp pains and cold, itchy sensations in those who used the topical CBD compared to those who used the placebo. No participants reported adverse side effects.
Conclusion: CBD may help with depression but more trials are needed.
Animal studies have shown some effect of CBD at relieving depression, possibly related to its strong anti-stress effect after either acute or repeated administration. 16
Conclusion: Topical CBD may help relieve inflammation and excessive sebum production associated with acne but more trials are needed.
6. Sleep disorders
Unlike THC, CBD has no psychoactive properties and will not give you a “high”. There is no evidence it has any abuse or dependence potential and to date, there is no evidence that it is associated with any serious side effects, according to the World Health Organization.
Animal studies have shown that CBD has a positive effect on serotonin levels in the brain, and serotonin. Low levels of serotonin are thought to play a key role in mood as well as pain. 11
Unfortunately, few human trials investigating the use of CBD as a single agent to relieve pain exist, with most trials using a combination of CBD and THC to relieve pain. Notably, Health Canada has approved a combination medication that contains both THC and CBD in a 1:1 ratio for the relief of central nerve-related pain in multiple sclerosis, and cancer pain that is unresponsive to optimized opioid therapy.
Instead, CBD has been credited with relieving numerous medical conditions, such as epilepsy, anxiety, inflammation, insomnia, and pain. Although “credited” does not mean proven. Because of the historical regulatory landscape, there are hardly any well-conducted trials backing up those claims, although research is expected to ramp up now that laws distinguish between hemp and marijuana.
Our skin has the highest concentration and amount of CB2 receptors of all other organs of the body. Several studies show that CBD oil has a high likelihood of treating certain skin conditions  like acne and eczema by encouraging abnormal cell death.
During bone metabolism, old bone material is replaced by new bones at a rate of about 10% per year  . Cannabinoids help facilitate this crucial process of maintaining strong, healthy bones over time.
5.3 Treat Lupus
CBD oil can help reduce the risk of age-related bone diseases like osteoarthritis and osteoporosis by blocking an enzyme that destroys the body’s bone-building compounds. In the case of these diseases, the body doesn’t create new bone and cartilage cells.
Hypothetically, opioids are prescribed to people with PTSD. However, opioids can be very addictive and put patients at risk of developing disorders from opioid use. Thankfully, CBD offers patients safer treatment options for those with PTSD without side effects.
Developed Western nations are commonly affected by atherosclerosis, which can lead to heart diseases or strokes. This chronic inflammatory disorder has been linked to diet and lifestyle. It involves the progressive depositing of immune cells that carry oxidized LDL, also known as atherosclerotic plaques.