The reason for applying the CBD oil beneath the tongue (known as using it sublingually) is, you guessed it, bioavailability. Rather than swallowing your CBD oils and sending it through the digestive system, let it soak into the blood vessels beneath the tongue for around 90 seconds. That way it gets into circulation much faster.
Since the bioavailability of CBD topicals is low, it’s a slower release means of consuming CBD. CBD effects will take around an hour to be asborbed and last for about five hours. Regardless of duration, if you’re looking for an external application then CBD topicals are the obvious way to go.
CBD and bioavailability
The CBD will generally take around thirty minutes to be absorbed properly, and take six hours to leave the bloodstream. This makes CBD oils a great way to dose if you only want to use CBD intermittently. You can take half your recommended dosage in the morning, and the other half in the evening.
When comparing oral CBD options it’s worth considering the carrier oil. The MCT (coconut) oil in our CBD Oral Spray helps mask the taste of the hemp for those who don’t like its earthy tones, while the hemp seed oil in our CBD Oral Drops works great with CBD to provide a full-bodied hemp experience.
You know what CBD is, and you’ve managed to decide on a means of taking it. All settled right? Well you actually still have to choose the strength of your CBD oils or CBD e-liquids, one of the most important factors. That’s why we’ve extensively polled our users to give you the best CBD experience.
Part of this response could be explained by the way that CBD acts in the brain. In low doses, CBD may act as an agonist to several receptor sites, meaning it acts similarly to surrounding molecules that normally bind to the receptor, enhancing the signalling of those receptor sites. At higher doses, however, too much activity at the receptor site can lead to an opposite effect, negating the beneficial effects of CBD.
Outside of these two disorders, CBD’s effectiveness in treating seizures is uncertain. Even with Epidiolex, it is uncertain whether the anti-seizure effects can be attributed to CBD or some other factor.
There are no guidelines for the appropriate use of CBD oil. CBD oil is usually delivered sublingually (under the tongue). Most oils are sold in 30-milliliter (mL) bottles with a dropper cap.
To determine an exact dose of CBD, remember that each drop of oil equals 0.05 mL of fluid. This means that a 30-mL bottle of CBD oil will have roughly 600 drops. If the concentration of the tincture is 1,500 mg/mL, one drop would contain 2.5 mg of CBD (1,500 mg ÷ 600 drops = 2.5 mg).
Many of these interactions are mild and require no adjustment to treatment. Others may require a drug substitution or the separation of doses by several hours.