Although blood tests are not nearly as common as urine tests for screening for CBD and cannabinoids, they can be used to detect THC metabolites. The reason they’re not the preferred method of drug screening is because of how quickly THC is eliminated from your bloodstream.
But does the duration of its effects influence how long it stays in your system for?
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How Long Does CBD Stay In Your Blood?
Your method of intake can influence how it affects you as well as for how long it lasts. Popular methods and forms of CBD include:
Furthermore, some tests are more effective at detecting THC and for longer periods of time. The type of drug screening you’re administered – and how long after you last took CBD – could influence whether it’s detectable.
There isn’t a simple answer for how long CBD stays in your system. It depends on a number of factors, such as how it was administered, the dosage, and the frequency of use.
It’s also worth noting that because CBD products are not regulated by the FDA, it’s possible that you could be taking CBD that is mixed with other cannabinoids, which could increase detectability. Also, it’s worth noting that the more frequently you use cannabis products, the wider detection windows become.
One study examined the potential drug interactions between a THC/CBD oromucosal spray and CYP450 inducers and inhibitors in various dose regimens. The study done on healthy male subjects showed that inducers of CYP3A4, an enzyme involved in the metabolism of CBD significantly reduced the peak plasma concentration of CBD. On the other hand, a CYP3A4 inhibitor nearly doubled the peak plasma concentration of CBD .
The amount of time CBD remains in the body depends on how much you took, how often you use it, and what form of CBD you’re using.
The lymphatic system plays a role in the process of absorbing fats and fat-soluble nutrients. Cannabidiol as a highly lipophilic compound — a compound that has the ability to dissolve or combine with lipids or fats — can be transported by the lymphatic system.
Does CBD Interact With Other Drugs?
CBD won’t be in your system for longer than 7 days after your last use — unless you’re a frequent user of CBD (more than 10 mg per day for several weeks). In this case, CBD may linger for up to two more weeks depending on how often you use it.
Topical application is best for localized symptoms, such as local inflammation and pain caused by arthritis. Strictly topical application of CBD works locally — the applied CBD product never reaches the bloodstream.
If you want to take a short break, increase your dose, switch from one method of consumption to another, or are simply curious about what happens to CBD after it enters the body — we provide you with all the answers.
Part of the topical administration is the transdermal application where CBD is administered into the skin but is absorbed by the skin to reach the systemic circulation.
Bottom line: Whether you’re ingesting CBD oil or CBD-infused edibles, it ultimately goes through the same lengthy digestive process, reducing the total CBD concentration in the bloodstream. With ingestion, it could take anywhere from one to two hours before the effects of CBD finally set in. From there, you may feel the effects for one hour to several hours, depending on the dose and your response to CBD.
We have some insight into how long CBD remains in the blood, but there is little research on how long CBD is detectable in urine. In a 2016 study published in the Journal of Pain, participants were given different types of CBD-rich cannabis products, including oils, capsules, and flower. Two hours after administration, urine samples from all 15 subjects tested positive for CBD. The researchers followed one participant after the last day of administration and found that CBD was no longer detectable in the urine after 24 hours.
It’s important to note that, while existing evidence shows us that CBD can definitely be detected in the body for a certain period of time, most drug tests specifically look for the presence of THC. Therefore, accurate information on how long CBD stays in the body remains limited compared with information on THC.
Inhalation is also an effective delivery method for CBD due to its rapid absorption and the efficiency of the lungs at transferring CBD into the bloodstream. Whether you’re smoking a high-CBD strain or taking a draw from a CBD vape pen, the interaction with the body remains the same. When CBD is inhaled, the cannabinoids are sent directly to the lungs, where they are rapidly absorbed into the bloodstream and put into circulation.
The sublingual method is considered to be more effective than ingestion. CBD oil can be consumed sublingually by placing a few drops under the tongue and holding it for two to four minutes, then using the tongue to rub it into the tissue under the tongue and on the inside of the cheeks before swallowing the remainder. Using this method, CBD is transferred to the bloodstream via the mucous membranes located in the mouth, completely bypassing the digestive system and liver.
Here, we’ll cover the existing research on CBD and its interaction with the human body as well as what factors can affect how long CBD stays in your system.
Inhalation, via CBD vapes or smokable flower, is also an effective delivery method for CBD. Photo by: Gina Coleman/Weedmaps