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how cbd works in the body

Can I take this if I am in antidepressants and suboxone?
Will it make me gain weight?
I struggle with lots of back pain , depression, anxiety and I have hard time sleeping. Will it be helpful?

2. McPartland JM, Matias I, Di Marzo V, Glass M. Evolutionary origins of the endocannabinoid system. Gene. 2006;370:64-74.doi:

CBD is a phytocannabinoid derived from the cannabis and hemp plant. CBD derived from hemp is currently the only cannabinoid readily accessible across the entire U.S. Unlike other cannabinoids, CBD does not bind to receptors in the endocannabinoid system.

CBD and your endocannabinoid system

Initially, research showed endocannabinoid receptors were only present in the brain and nerves, but have since been found throughout the entire body including our skin.₃ Today we know that the endocannabinoid system is involved in a number of processes including pain, memory, mood, appetite, stress, sleep, metabolism, immune system, and our reproductive function.₄,₅ Endocannabinoids are arguably one of the most widespread and versatile molecules.

At the end of the day, CBD is an incredible herbal supplement!


“CBD modulates non cannabinoid receptors as well. It directly activates the 5hT (serotonin receptor and acts as an atypical antipsychotic), binds directly to TRPV1 (Pain, inflammation, hypothalamus control). It blocks GPR55 (a 3rd cannabinoid type receptor) which through a series of events, decreases the breakdown of bone, acts as an antiseptic, prevents cancer cells from growing and many other things. CBD also changes the shape of the CB1, preventing THC from directly binding to it. (This is why balanced strains of cannabis give less anxiety and paranoia; the CB1 receptors are not overstimulated by THC.)”

Green Wellness Life, we are not doctors. We can’t diagnose, treat, or prescribe any ailments. Still, we conduct diligent research into the latest studies, user testimonials, and trend to be able to provide you with most accurate and up-to-date information possible on CBD. We want you to be informed so that you can make the best possible decisions for your health. If you have questions about CBD in general or you’d like to know which CBD products may be best for you, feel free to contact us by calling (888) 772-7875 or filling out a contact form. We’re here to help!

The human body is a complex machine, and the way it interacts with any compound, including Cannabidiol (CBD) can be even more so. We’ve only known about the system in our body that cannabinoids are part of since the 1990’s so there is definitely so much more to learn! Nonetheless, we’ve compiled and broken down some of the basic science we do know below.

CBD is extracted as an oil from cannabis through a number of different extraction processes. CBD oil is then utilized in a variety of different products ranging from capsules to tinctures, edible gummies, and more. All cannabinoids, including CBD, produce effects in the body by attaching to certain receptors belonging to the endocannabinoid system.

What is the Endocannabinoid System?

Maccarrone M, Bab I, Bíró T, et al. Endocannabinoid signaling at the periphery: 50 years after THC. Trends Pharmacol Sci. 2015;36(5):277-296.doi:10.1016/

The discovery of the endocannabinoid system within the body is relatively new. The system was discovered in the 90’s when researchers set out to study a series of plant-like molecules produced by the human body. The human body produces cannabinoids known as endogenous cannabinoids. Examples of endogenous cannabinoids (endocannabinoids) include n-arachidonoyl dopamine (NADA), 2-arachidonoylglycerol (2-AG), anandamide, and virodhamine (OAE).

The endocannabinoid system (ECS) plays a very interesting and varied role within the body. At its most basic, the endocannabinoid system is a huge network of cannabinoid receptors which are spread through the body. The human endocannabinoid system releases cannabinoids that interact with receptors found in virtually all of the tissues in our bodies. You can also take in phyto-cannabinoids (CBD) in addition to those compounds that your body produces to help boost this system. The role of the endocannabinoid system is to bring balance to our tissues, including the heart, digestive, endocrine, immune, nervous, and reproductive systems. In short, it’s working to keep you in neutral. Neutral means different things in different areas of your body, which is possibly one of the very best things about the compound – it can have a different impact on different receptors in your body.

Endocannabinoids operate differently when compared to other neurotransmitters like serotonin or dopamine. Endocannabinoids are not synthesized in advance and stored. Rather, they are produced on demand as needed. Endocannabinoids are also hydrophobic. This means their effects are localized since they can’t travel very far.