“There is a great deal of interest in the possible therapeutic effects of CBD, but there is very little evidence of efficacy,” said Dr. J Hampton Atkinson, co-director of the Center for Medical Cannabis Research (CMCR) at the University of California, San Diego. CBD may have health benefits, but the lack of research in this area means there just aren’t enough data points to support most of the anecdotal claims. Along that same line, the lack of research also means the potential health risks of consuming CBD are unclear.
Every variety of the cannabis family produces cannabinoids, including hemp. While CBD and THC are the most well-known cannabinoids, there are many different types, and only recently have significant resources been poured into their study. Our brains have specific receptors designed to accept cannabinoids, known as CB1 and CB2. These receptors are responsible for the assimilation of cannabinoid molecules into your system, resulting in the psychoactive and immune responses correlated with cannabis consumption.
Research on CBD
Some research suggests that CBD may reduce anxiety and self-deprecating thoughts, and there’s evidence that CBD has antipsychotic effects in people with schizophrenia. But other studies show no significant benefit of CBD over a placebo.
In the last few years, there have been many advances in cannabis processing and consumption methods. Concentrated products such as oil and rosin (a sap-like product extracted via heat and pressure) have allowed for cleaner ingestion methods, such as vaporization, to become more widespread. These new technologies have brought more consistent, identifiable dosages to patients and enthusiasts alike, while potentially enabling safer methods of consumption. Finally, more accurate and detailed studies of cannabis effects and usage are underway, as prohibition continues to be challenged.
Within the CMCR, there is also “much interest in the possible anti-inflammatory effects of CBD, for use in arthritis of various types, including knees and hands,” Atkinson said. Recent in vitro research with human cell lines afflicted with rheumatoid arthritis has suggested that CBD treatment may help reduce inflammation.
Combine THC and CBD to fully enjoy the entourage effect .
According to research , when CBD is introduced to our endocannabinoid system, it prevents the body from absorbing a pain-regulating compound known as anandamide, an endogenous cannabinoid. Inhibiting the absorption of this compound shunts excess quantities into the bloodstream that in turn, may reduce pain. CBD may also target specific spinal receptors helping to suppress pain and inflammation. In both human and animal models, CBD seems to have a variety of anti-inflammatory properties.
What is CBD?
(Photo by: Gina Coleman/Weedmaps)
Harlequin : This cultivar was bred by crossing classic landraces from Nepal, Switzerland, and Thailand. Its consistent 5:2 CBD to THC ratio ranks it among CBD-rich staple cultivars.
CBD fits the definition of a psychoactive substance as it can subtly alter perception and mood. However, it’s important to reiterate that unlike weed, CBD does not cause intoxication. CBD is a non-intoxicating substance, so it cannot stimulate the level of sensory and psychological effects that THC does.
Side effects of CBD include nausea, fatigue and irritability. CBD can increase the level in your blood of the blood thinner coumadin, and it can raise levels of certain other medications in your blood by the exact same mechanism that grapefruit juice does. A significant safety concern with CBD is that it is primarily marketed and sold as a supplement, not a medication. Currently, the FDA does not regulate the safety and purity of dietary supplements. So, you cannot know for sure that the product you buy has active ingredients at the dose listed on the label. In addition, the product may contain other (unknown) elements. We also don’t know the most effective therapeutic dose of CBD for any particular medical condition.
Some CBD manufacturers have come under government scrutiny for wild, indefensible claims, such that CBD is a cure-all for cancer, which it is not. We need more research but CBD may be prove to be an option for managing anxiety, insomnia, and chronic pain. Without sufficient high-quality evidence in human studies we can’t pinpoint effective doses, and because CBD is currently is mostly available as an unregulated supplement, it’s difficult to know exactly what you are getting. If you decide to try CBD, talk with your doctor — if for no other reason than to make sure it won’t affect other medications you are taking.
CBD stands for cannabidiol. It is the second most prevalent of the active ingredients of cannabis (marijuana). While CBD is an essential component of medical marijuana, it is derived directly from the hemp plant, which is a cousin of the marijuana plant. While CBD is a component of marijuana (one of hundreds), by itself it does not cause a "high." According to a report from the World Health Organization, "In humans, CBD exhibits no effects indicative of any abuse or dependence potential…. To date, there is no evidence of public health related problems associated with the use of pure CBD."
Is CBD safe?
CBD has been touted for a wide variety of health issues, but the strongest scientific evidence is for its effectiveness in treating some of the cruelest childhood epilepsy syndromes, such as Dravet syndrome and Lennox-Gastaut syndrome (LGS), which typically don’t respond to antiseizure medications. In numerous studies, CBD was able to reduce the number of seizures, and, in some cases, it was able to stop them altogether. Videos of the effects of CBD on these children and their seizures are readily available on the Internet for viewing, and they are quite striking. Recently the FDA approved the first ever cannabis-derived medicine for these conditions, Epidiolex, which contains CBD.
Cannabidiol (CBD) has been recently covered in the media, and you may have even seen it as an add-in booster to your post-workout smoothie or morning coffee. What exactly is CBD? Why is it suddenly so popular?
CBD is readily obtainable in most parts of the United States, though its exact legal status is in flux. All 50 states have laws legalizing CBD with varying degrees of restriction, and while the federal government still considers CBD in the same class as marijuana, it doesn’t habitually enforce against it. In December 2015, the FDA eased the regulatory requirements to allow researchers to conduct CBD trials. Currently, many people obtain CBD online without a medical cannabis license. The government’s position on CBD is confusing, and depends in part on whether the CBD comes from hemp or marijuana. The legality of CBD is expected to change, as there is currently bipartisan consensus in Congress to make the hemp crop legal which would, for all intents and purposes, make CBD difficult to prohibit.
CBD is commonly used to address anxiety, and for patients who suffer through the misery of insomnia, studies suggest that CBD may help with both falling asleep and staying asleep.