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cbd oil interstitial cystitis

Although no medicinal claims can be made about over the counter CBD products, anecdotally people have suggested that CBD may have helped them with their own:

In this study, human bladders were dissected at the detrusor and urothelial levels. (You may be interested in a previous post I wrote entitled Layers of the Bladder and What Can Go Wrong to find out what exactly the detrusor and urothelium do.) The study confirmed the presence of CB1 and CB2 receptors in both layers of the human bladder and suggested them as “a target for drugs acting on the symptoms of interstitial cystitis/painful bladder syndrome”.

Unless you’ve been living entirely off-grid for the last five years, you’ve almost certainly heard of CBD and will be aware of its rising popularity within the complementary health sector. Just in case all the hype has passed you by, allow me to provide a brief explanation!

Fascinating though all that is, I know what you really want to know: can CBD help with interstitial cystitis or other bladder pain conditions? Given the strict rules around making medicinal claims about CBD products, I won’t answer that directly, but I WILL tell you a little about the endocannabinoid system and direct you to some bladder-specific studies.

Endocannabinoids are molecules made by the human body to maintain bodily homeostasis. They are made by the body regardless of whether or not we use cannabis and are important in regulating processes like:

This pilot, randomised, double-blind, placebo-controlled, phase II clinical trial demonstrated that cannabis based medicine containing CBD and THC provided better protection against chemotherapy induced nausea and vomiting than antiemetic treatment alone. Acute and delayed chemotherapy induced nausea and vomiting have been found to significantly reduce patients’ quality of life.

For more information on how CB2 receptors and the ECS works, please see our page on endocannabinoids here .

According to Dr. Curtis Nickel, a urologist—who prescribes cannabis for urologic chronic pelvic pain—vaping, tinctures, and edibles are all considered preferential to his patients and are easier to measure dosages with over smoking it. He generally recommends starting “low and go slow” and that patients start with a 1:1 ratio of CBD to THC. He encourages patients to carefully experiment with dosing to get the desired effect ( 3 ). Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD) are the two most popular cannabinoids, or chemical compounds, found in marijuana.

Recommendations for Relieving Bladder Pain with Cannabis

Even though Interstitial Cystitis (IC), a very painful bladder disease, is not specifically named on state medical marijuana card requirements, many patients are able to get relief from cannabis. Many states do list persistent muscle spasms and chronic pain as qualifying medical conditions, which are the major symptoms of interstitial cystitis. However, an individualized consultation with a qualified physician is necessary to make an appropriate determination.

Dr. Nickel cites the following as average dosages to work up to depending on the individual ( 3 ):

“Interstitial cystitis and pelvic pain patients have used medical marijuana for years. Several years ago, we did a study on MMJ and IC with 492 patients reporting that they have used it. 17% reported that it resolved their symptoms completely, while 64% reported that it reduced their symptoms by 50%. It improved frequency and urgency for 80% of patients. It was most effective for pain management…with 32% reporting that their pain resolved while using it. Most used it daily or weekly. 92% say that they will continue to use it,” Osborne said (4).