Once endocannabinoids have done their work, they get broken down by enzymes to prevent overaccumulation.
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Before receiving the FDA’s approval, Epidiolex went through three randomized, double-blind, placebo-controlled clinical trials examining 516 patients with either syndrome. When administered along with other medications, Epidiolex successfully reduced the participant’s frequency of seizures compared to the placebo group. Besides, CBD improved other associated symptoms for the participants, such as sleep and anxiety.
It sends signals to various bodily systems through its chemical messengers called endocannabinoids to do this. These molecules bind to the cannabinoid receptors which occur in the brain and throughout the body. By doing so, endocannabinoids help the endocannabinoid system to maintain healthy functioning of an individual.
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While CBD oil may provide some relief from seizures, it should always be taken with caution and under guidance from a medical professional. This is because of:
It is always positive to learn about a new treatment for epilepsy, and the potential benefits of CBD oil for seizures in adults and children are exciting. However, we are still learning about how CBD affects people with epilepsy, so until we know more it should not be seen as a replacement for standard treatments.
CBD oil may help to stop seizures by activating certain cells called CB1 receptors. These cells are found in the nervous systems and in parts of the brain that are related to memory. Researchers are still not exactly sure how CBD affects seizures, but it may help protect brain cells against damage or from becoming ‘over excited’.
Side effects and interactions between CBD oil and seizure medicine
Here is everything we know about CBD oil and seizures.
People have been using cannabis (also known as marijuana) to treat epilepsy for centuries. In the United States it only became legal to take marijuana products for medical reasons relatively recently. And, in 2018, a CBD oil for seizures called Epidiolex was approved by the FDA to treat certain epilepsy syndromes (CBD is a chemical found in cannabis plants).
It is possible to purchase CBD oil for seizures in adults from health food stores in most, but not all, US states (although the rules vary, and you should always check with your healthcare provider). Many companies promote the use of CBD oil for a range of conditions – from anxiety to insomnia to chronic pain – and it may be marketed as a solution to epilepsy too.
The medication was approved after several trials showed a significant reduction in seizures for people with these conditions (in combination with their existing anti-epilepsy drugs).
CBD doesn’t — another substance in marijuana called THC does that. If you use a CBD product, check the label and make sure that’s the only cannabinoid listed. In states where marijuana is legal, some companies put product information online that lists the amount of each ingredient.
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How Do You Take It?
You can take CBD oil by itself by mouth, or use one of many products that has it as an ingredient. These include pills, chewable gels, “tinctures” you drop under your tongue, vape cartridges you breathe in, creams on your skin, and foods like chocolate bars. The amount and quality of CBD in these products can be very different.
It’s short for cannabidiol, and it’s a natural compound found in both marijuana and hemp plants. There’s some evidence that it might help treat pain, seizures, and some other health problems. But much more research is needed for doctors to know for sure what it can do.
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