CBD Oil For Ankylosing Spondylitis

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Cannabis treatment has been shown to have anti-inflammatory benefits and help treat common symptoms of ankylosing spondylitis (AS) such as pain.Read more! Ankylosing Spondylitis is a rare condition effecting mostly men that can cause problems with the spine. Learn more about how CBD can help with AS problems. Your access to this site has been limited by the site owner If you think you have been blocked in error, contact the owner of this site for assistance. If you are a WordPress user with

Can Cannabis Help Ankylosing Spondylitis?

Cannabis treatment has been shown to have anti-inflammatory benefits and help treat common symptoms of ankylosing spondylitis (AS) such as pain . Currently, no studies have been published on cannabis as a treatment option specifically for AS. That being said, a randomized controlled trial is underway which is exploring the effects of the prime molecules in cannabis, such as CBD and THC , on AS symptoms.

Cannabis has been shown to help reduce pain associated with conditions that share symptoms with AS such as fibromyalgia , chronic back/neck pain , osteoarthritis , rheumatoid arthritis , migraines , and menstrual pain .

Reviews of studies have also confirmed that there is an overall positive association between cannabis use and pain relief. That being said, these studies examined the pain relief properties of cannabis in specific conditions, and not specifically for AS-related pain.

Additionally, there are many types of cannabis strains. Research is yet to confirm whether specific strains are more or less effective for treating specific diseases.

How Cannabis Works on Ankylosing Spondylitis

The endocannabinoid system (ECS) exists in all vertebrates and helps regulate crucial functions such as sleep, pain, and appetite. The human body produces its own cannabinoids, which modulate and activate its various functions, but as its name suggests, the endocannabinoid system can also be modulated and activated by cannabinoids found in the cannabis plant. Because the entire system was only discovered in the past 30 years, scientists still have much to learn about the myriad ways cannabis affects the human body.

The endocannabinoid system and its CB1 and CB2 receptors regulate pain and inflammatory processes. Cannabinoid receptors are dispersed around different areas of the body. Both CB1 and CB2 receptors can be influenced by cannabis.

CB1 receptors are abundant in the brain and central nervous system. They are found in regions of the peripheral and central nervous system where pain signaling occurs, and therefore modulates pain. Activating CB1 receptors may, therefore, help with pain relief.

CB2 receptors , on the other hand, are primarily expressed on immune cells. They are also found in the brain but in far lower concentrations and have also been found on bone and connective tissue cells . The activation of CB2 receptors has been shown to decrease several markers of inflammation.

Ankylosing spondylitis causes pain and inflammation, which are two functions the endocannabinoid system plays a role in regulating. The stimulation of the endocannabinoid system may, therefore, help with reducing symptoms such as pain and inflammation caused by AS.

Research on Ankylosing Spondylitis and Cannabis

Current research has established the positive benefits cannabis has for pain in conditions such as rheumatoid arthritis and fibromyalgia, which share some similarities to ankylosing spondylitis.

Cannabis has been approved for Crohn’s disease and ulcerative colitis, which are conditions that fall under a group of diseases known as PAIR that AS is also categorized under ( psoriatic arthritis , ankylosing spondylitis, IBD ( crohn’s disease and ulcerative colitis ), and reactive arthritis).

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The following studies — although not on AS specifically — shed light on the potential of cannabis to reduce symptoms of AS as it does in related conditions.

  • This systematic review looked at the results of 28 studies on cannabis and chronic pain. The researchers concluded that “there was moderate-quality evidence to support the use of cannabinoids for the treatment of chronic pain.” Overall, these results show that cannabis use tends to be associated with reductions in pain. That being said, the sample sizes of the selected studies were small.
  • One study investigated the direct effects of cannabis on Crohn’s disease. Twenty-one out of 30 patients experienced significant improvements in their disease activity, use of medication, and need for surgery before and after cannabis use.
  • In a 2018 report , the results of a randomized double-blind placebo controlled study showed that cannabidiol-rich treatment of patients with ulcerative colitis helped 59% of them experience remission rates of 28%. The study participants received a CBD-rich extract that contained 4% THC.
  • One randomized controlled trial published in 2008 found that Nabilone (which mimics THC) improved pain from fibromyalgia compared to placebo over four weeks.
  • In a 2006 randomized controlled trial , Sativex (1:1 THC:CBD) was shown to decrease pain in participants with rheumatoid arthritis. Out of 58 patients, 31 were given Sativex and 27 were given a placebo. Researchers found that patients using Sativex experienced decreases in pain on movement and improved sleep.
  • In a randomized controlled trial , researchers administered inhaled cannabis containing 9.4% THC to patients with neuropathic pain. The treatment resulted in significant reductions in pain compared to the placebo group.

Cannabis appears to be effective for relieving neuropathic pain, reducing inflammation, and decreasing pain from rheumatoid arthritis, fibromyalgia, and improving other conditions related to AS such as Crohn’s disease and ulcerative colitis.

While cannabis is beneficial for other conditions, more clinical research that examines the effectiveness of cannabis in AS should be done.

CBD and Ankylosing Spondylitis

Human and animal studies show CBD is effective for reducing pain in several conditions. Animal studies — but not human studies — show CBD helps reduce arthritic pain. AS is a form of arthritis, and therefore CBD may help with symptoms in humans.

  • The results from a 2018 review showed that CBD was effective for relieving neuropathic pain, cancer pain, and fibromyalgia pain.
  • In one 2017 study , researchers looked at how CBD affects joint degeneration and inflammation. Researchers induced osteoarthritis in rats, and then administered a CBD treatment and examined the effects. CBD was found to prevent further pain development and nerve damage in joints.
  • One 2014 review on the existing animal research concluded that CBD may be effective for treating osteoarthritis.
  • A 2011 study looked at how CBD affects the response of pain receptors in rat models. Researchers found that CBD was able to decrease inflammatory pain.

The promising research on CBD and pain has given scientists enough confidence to pursue a clinical trial to confirm the effects CBD has on AS patients.

In a double-blind randomized placebo-controlled study , researchers from Denmark will be testing whether CBD helps chronic pain in patients with rheumatoid arthritis or AS. An oral CBD treatment in the experiment group will be compared to a placebo over 12 weeks. There will be a 12-week observational period that will follow with the add-on of THC for CBD ‘non-responders’. Physiological and psychological markers will be collected after 12 and 24 weeks of treatment with a final follow up at 36 weeks.

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The aim of the study is to test whether CBD and THC help with pain and also to assess the effect of cannabis treatments on cognitive function and sleep. Testing other factors besides pain will help researchers understand the viability of cannabis as a treatment for both conditions.

CBD is effective for pain, but we need to wait for the results of this CBD-AS trial to be published for a definite answer.

Potential side effects of cannabis use

Cannabis is well-tolerated and safe to use as a treatment for pain.

Cannabis has been shown to cause short-term side effects such as impaired concentration, fatigue, changes to mood, appetite, and perception.

The long-term side effects of cannabis are largely contingent on the extent of one’s use, the age at which one starts using cannabis, and genetic predispositions to developing mental health conditions such as schizophrenia, substance abuse disorder, and bipolar disorder).

When considering the use of cannabis for symptoms of AS, it’s critical to consult with your doctor before starting treatment.

CBD Hemp Oil for Ankylosing Spondylitis

Arthritis is a prevalent chronic health problem in Canada, with around 6 million Canadians currently suffering from this condition. It’s been estimated that by 2040, 24 percent of Canada’s population will have arthritis. It doesn’t target a specific age group, but your chances of getting the disease increases as you grow older.

There are over 100 known types of arthritis today. All of them cause joint inflammation and stiffness which can lead to permanent damage if left untreated for too long. What makes this disease highly problematic is that once you have it, it stays with you for the rest of your life.

Other kinds of arthritis can even cause problems to the eyes, heart, or lungs. One of these more dangerous types is Ankylosing Spondylitis.

What is Ankylosing Spondylitis?

Ankylosing Spondylitis or AS mainly affects the spine. Given enough time, it will slowly fuse parts of the vertebrae together until you are hunched. It’s not unusual for the pelvis to be affected as well. In more severe cases, this disease can also spread to the shoulders, ribs and other joints in the body.

Some of AS’ symptoms are as follows:

  • Pain and stiffness in the lower back, pelvis, legs, or shoulders
  • Increased pain in the morning or after being inactive for long periods of time
  • Blurry vision and heightened sensitivity to light

AS can lead to other complications, such as

  • Inflammation in the eyes
  • Restricted breathing
  • Increased likeliness of cancer
  • Heart impairment

It is a rare condition that is more likely to occur in men. Unlike most forms of arthritis which are more commonplace in older people, young adults are more susceptible to this disease.

But like most other arthritis types, Ankylosing Spondylitis doesn’t have a known cure yet. However, there are medications that you can take to prevent its symptoms from getting worse or at least slow its progress down.

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If you’re looking for something else aside from opioids and other pharmaceuticals, one of the most popular natural options is CBD oil.

How CBD Oil Can Help With AS

In recent years, CBD oil use has become commonplace among Canadians looking for an alternative to pharmaceuticals. This is because CBD & CBD hemp products don’t induce the psychoactive effects that cannabis does, thanks to the lack of tetrahydrocannabinol or THC.

CBD’s Health Benefits

The benefits of CBD can include:

CBD’s famous pain-relieving and anti-inflammatory properties have made it attractive to people who need help with pain management.

CBD and the ECS

To understand how CBD, or cannabidiol, can relieve arthritis pain, we must first know about the endocannabinoid system or ECS, which we are all born with.

CBD helps your body by interacting with your ECS, which has receptors that receive chemical signals and assist your cells in responding to different stimuli in the body. While the ECS can send pain-relieving signals without the help of CBD, the substance enhances the effects that it has on you.

We offer all Canadians free phone and video appointments with one of our healthcare practitioners where they can inquire about obtaining a medical cannabis prescription.
If you would like to book your free appointment, you can here.

CBD’s Special Anti-Inflammatory Effect

For a long time, it was assumed that CBD’s effectiveness at reducing inflammation was thanks to its interactions with the ECS receptors. However, there’s a recent study by the Brain and Spine Institute in France that reveals that CBD didn’t need the receptors. The chemical already has inherent antioxidant properties and suppresses an enzyme that stimulates inflammation in the body.

For people with Ankylosing Spondylitis, which has severe inflammations, this property is immensely helpful in slowing down its symptoms.

Consult a Physician First

If you are interested in CBD oil for relieving your Ankylosing Spondylitis symptoms, it’s safer to consult a trusted physician first on proper dosages and to make sure that it is not conflicting with any ongoing medications and treatments you have. Your healthcare provider should always be updated on your progress and any side effects you may be feeling.

Apollo’s Cannabis Clinic physicians are here and offer free appointments to all Canadians, 7 days a week.

To get safe and high-quality CBD, be sure to buy tested and certified products from trusted sources. Book an appointment with our dedicated doctors today and find out more about how Apollo can help.

arthritis.ca/about-arthritis/what-is-arthritis/arthritis-facts-and-figures
webmd.com/arthritis/what-is-ankylosing-spondylitis#1
verywellhealth.com/what-is-the-endocannabinoid-system-4171855
icm-institute.org/en/actualite/anti-inflammatory-effect-of-cannabidiol-a-non-psychoactivecomponent-of-cannabis/
healthline.com/health/cbd-and-drug-interactions-what-you-need-to-know

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