Cannabis treatment in people with certain forms of epilepsy has been more promising. The only FDA-approved cannabis-based drug is Epidiolex, a CBD oral solution for treating two rare and severe forms of epilepsy. A recent clinical trial found that Epidiolex reduced convulsive seizures by 50% in children with Dravet syndrome, a type of epilepsy, MedPage Today reported.
It’s important to know that the research in this area is in its infancy, partly because we haven’t really understood much about CBD until relatively recently,” said Marcel Bonn-Miller, an adjunct assistant professor at the University of Pennsylvania Perelman School of Medicine. He pointed out that the classification of marijuana as a Schedule 1 drug by the DEA makes it difficult to get material to use in laboratory studies. Schedule 1 drugs have a high potential for abuse, according to the DEA, and are illegal under federal law.
The popularity of medical marijuana is soaring, and among the numerous products consumers are seeking are CBD, or cannabis oils.
Why do people use cannabis oil?
Because of this classification, it’s not easy for researchers to get their hands on the drug. “That’s not to say you can’t do it, but there are hoops you need to jump through that can be a pain, which may deter researchers from going into this space,” Bonn-Miller said. “Relatively speaking, it’s a small group of people in the U.S. that do research on cannabinoids in humans.”
The physiological effects of cannabinoids can vary widely from person to person, and also depend on how they’re consumed. That lack of predictability is one of the reasons why cannabis oil is a challenging candidate for developing into a medicine, Ward told Live Science.
Simply put, cannabis oil is the concentrated liquid extract of the marijuana plant, Cannabis sativa.
It’s a little more uniform when the product is absorbed by smoking or vaping the oil, Ward said. But, “there are obvious concerns about smoking something.” A 2007 review published in the journal JAMA Internal Medicine found that smoking marijuana resulted in similar declines in respiratory system health as smoking tobacco. A similar review published in 2014 in The American Journal of Cardiology found that marijuana smoke inhalation can increase the chances of heart attack or stroke. Neither review analyzed the effects of vaping cannabis oil alone, so it’s unclear if it has the same health risks as smoking other marijuana products.
The defining difference between hemp and marijuana is their psychoactive component: tetrahydrocannabinol, or THC. Hemp has 0.3% or less THC, meaning hemp-derived products don’t contain enough THC to create the “high” traditionally associated with marijuana.
As interest in other cannabinoids, like cannabigerol, or CBG – which some are touting as the new CBD – continues to grow, so too grows the need for further medical research into cannabis.
Though 15 states have now legalized recreational marijuana, it remains illegal federally in the United States. Technically, those in possession of marijuana in a legal weed state can still be punished under federal law, and traveling across state borders with cannabis is prohibited.
CBD is a compound found in cannabis. There are hundreds of such compounds, which are termed “cannabinoids,” because they interact with receptors involved in a variety of functions like appetite, anxiety, depression and pain sensation. THC is also a cannabinoid.
While 67% of U.S. adults support marijuana legalization, public knowledge about cannabis is low. A third of Americans think hemp and marijuana are the same thing, according to the National Institutes of Health, and many people still search Google to find out whether cannabidiol – a cannabis derivative known as CBD – will get them high, as marijuana does.