When it comes CBD and antibiotics, the information about the potential for interference is limited. While there is a potential for CBD to interact or interfere with some prescription medications, it is not clear if it has any impact on antibiotics.
Antibiotics are generally used to help with infections or certain sicknesses that may be caused by bacteria. Since studies into CBD and it’s interactions with prescription medications are limited, you may want to consider waiting to use CBD until you are no longer required to take an antibiotic.
CBD and Antibiotics
When your doctor prescribes an antibiotic to address a specific health concern, you may have questions about interference from other things you use or take in your life. A common concern may relate to the use of cannabidiol, or CBD, and antibiotics.
CBD is a supplement that may be used for a myriad of purposes. In many cases, it is used as natural pain relief or a method of relaxing. Since one of the potential effects of CBD is drowsiness, it is ideal to ensure that it is used in a safe environment.
If you are unsure about the possible interactions with your medications, then you should discuss your concerns with a medical doctor. Antibiotics are usually given for a short-term ailment and you will want to follow your doctor’s instructions in relation to the use of your prescription medication. Since you may only need the medication for a few days or a week, you can avoid any risk of interference from CBD supplements or products by waiting until you do not need the antibiotic.
Researchers from Penn State College of Medicine evaluated existing information on five prescription CBD and delta-9-tetrahydrocannabinol (THC) cannabinoid medications: antinausea medications used during cancer treatment (Marinol, Syndros, Cesamet); a medication used primarily for muscle spasms in multiple sclerosis (Sativex, which is not currently available in the US, but available in other countries); and an antiseizure medication (Epidiolex). Overall, the researchers identified 139 medications that may be affected by cannabinoids. This list was further narrowed to 57 medications, for which altered concentration can be dangerous. The list contains a variety of drugs from heart medications to antibiotics, although not all the drugs on the list may be affected by CBD-only products (some are only affected by THC). Potentially serious drug interactions with CBD included
Absolutely. Inhaled CBD gets into the blood the fastest, reaching high concentration within 30 minutes and increasing the risk of acute side effects. Edibles require longer time to absorb and are less likely to produce a high concentration peak, although they may eventually reach high enough levels to cause an issue or interact with other medications. Topical formulations, such as creams and lotions, may not absorb and get into the blood in sufficient amount to interact with other medications, although there is very little information on how much of CBD gets into the blood eventually. All of this is further complicated by the fact that none of these products are regulated or checked for purity, concentration, or safety.
CBD can alter the effects of other drugs
Products containing cannabidiol (CBD) seem to be all the rage these days, promising relief from a wide range of maladies, from insomnia and hot flashes to chronic pain and seizures. Some of these claims have merit to them, while some of them are just hype. But it won’t hurt to try, right? Well, not so fast. CBD is a biologically active compound, and as such, it may also have unintended consequences. These include known side effects of CBD, but also unintended interactions with supplements, herbal products, and over-the-counter (OTC) and prescription medications.
While generally considered safe, CBD may cause drowsiness, lightheadedness, nausea, diarrhea, dry mouth, and, in rare instances, damage to the liver. Taking CBD with other medications that have similar side effects may increase the risk of unwanted symptoms or toxicity. In other words, taking CBD at the same time with OTC or prescription medications and substances that cause sleepiness, such as opioids, benzodiazepines (such as Xanax or Ativan), antipsychotics, antidepressants, antihistamines (such as Benadryl), or alcohol may lead to increased sleepiness, fatigue, and possibly accidental falls and accidents when driving. Increased sedation and tiredness may also happen when using certain herbal supplements, such as kava, melatonin, and St. John’s wort. Taking CBD with stimulants (such as Adderall) may lead to decreased appetite, while taking it with the diabetes drug metformin or certain heartburn drugs (such as Prilosec) may increase the risk of diarrhea.
CBD has the potential to interact with many other products, including over-the-counter medications, herbal products, and prescription medications. Some medications should never be taken with CBD; the use of other medications may need to be modified or reduced to prevent serious issues. The consequences of drug interactions also depend on many other factors, including the dose of CBD, the dose of another medication, and a person’s underlying health condition. Older adults are more susceptible to drug interactions because they often take multiple medications, and because of age-related physiological changes that affect how our bodies process medications.
Studies into how antibiotics work within our bodies have shown that certain medications can interfere with their efficacy, and as such, you should always consult your doctor before combining antibiotics with any other medicines.
Now, it is essential that we make it clear from the start that this isn’t a common occurrence, nor does it mean that those on antibiotics must not consume CBD at the same time. However, what it does say is that a doctor MUST be consulted before adding either CBD or antibiotics to your list of medications.
Can CBD and Antibiotics Be Taken Together?
Among the many different drugs that can have an impact on the Cytochrome system are antibiotics, steroids, anesthetics, antidepressants , beta-blockers, and many more! But what exactly does this mean for CBD users?
CBD has actually been shown to inhibit the Cytochrome P-450 system, which can alter the way the system metabolizes certain other drugs that pass through – in this case, antibiotics. In other words, there is a chance that those consuming antibiotics and CBD at the same time could be at risk of taking less or more antibiotics than required, which could be dangerous and even lead to an overdose.
As we now know, CBD works with our endocannabinoid system to improve the production of natural cannabinoids. As such, it is natural to assume that CBD may interact with antibiotics – as well as other medications – in some way.