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can you overdose on cbd oil

El-Alfy AT, Ivey K, Robinson K, et al. Antidepressant-like effect of delta9-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa L. Pharmacol Biochem Behav 2010;95(4):434-42. View abstract.

Ligresti A, Moriello AS, Starowicz K, et al. Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma. J Pharmacol Exp Ther 2006;318(3):1375-87. View abstract.

Pretzsch CM, Freyberg J, Voinescu B, et al. Effects of cannabidiol on brain excitation and inhibition systems; a randomised placebo-controlled single dose trial during magnetic resonance spectroscopy in adults with and without autism spectrum disorder. Neuropsychopharmacology. 2019;44(8):1398-1405. View abstract.

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Campos AC, Guimaraes FS. Activation of 5HT1A receptors mediates the anxiolytic effects of cannabidiol in a PTSD model. Behav Pharmacol 2009;20:S54.

Lattanzi S, Trinka E, Striano P, et al. Cannabidiol efficacy and clobazam status: A systematic review and meta-analysis. Epilepsia. 2020;61(6):1090-1098. View abstract.

Yadav V, Bever C Jr, Bowen J, et al. Summary of evidence-based guideline: complementary and alternative medicine in multiple sclerosis: report of the guideline development subcommittee of the American Academy of Neurology. Neurology. 2014;82(12):1083-92. View abstract.

Leweke FM, Kranaster L, Pahlisch F, et al. The efficacy of cannabidiol in the treatment of schizophrenia – a translational approach. Schizophr Bull 2011;37(Suppl 1):313.

One such study was published in 2013 in the journal Current Drug Abuse Review as researchers reported on a phenomenon called Cannabinoid Hyperemesis Syndrome. This newly identified clinical syndrome coincides with chronic cannabis abuse and frequent episodes of nausea and vomiting, according to the authors of the study, all of whom are physicians. The researchers classified the prevalence of the syndrome as unknown, so further studies are needed to understand if such side effects are rare.

Cannabidiol (CBD) has become one of the most popular products in the entire cannabis industry, showing up in local coffee shops, pharmacies, and legal marijuana dispensaries. Despite the explosive popularity of CBD, there is still a lot of confusion about what CBD is and how it affects humans. For example, some may wonder: Can you overdose on CBD?

Can CBD make you sick?

Anecdotal evidence suggests that CBD oil can help treat pain and seizures in dogs, and that it has beneficial anti-inflammatory, anti-nausea, anti-anxiety, and anti-cancer properties, just as has been observed in humans. CBD may also help improve appetite and promote heart health in dogs, and many CBD-infused dog treats and CBD oil for dogs are readily available on the market.

In short, probably not, but there are associated risks. CBD is recognized as having a number of anti-inflammatory, anti-anxiety, and neuroprotective qualities, many of which can have positive effects on a broad range of health conditions. However, it’s still important to fully grasp not only the positive ways CBD can affect you, but also any of the potential side effects that may accompany the cannabinoid.

Regardless of the CBD product you’re taking, the answer is still the same. If you’re wondering, “Can you overdose on CBD gummies?”, the answer is no. When you eat a CBD gummy, your body will metabolize the CBD differently than it will if you smoke or vape CBD. While this could change how long it takes the CBD to go into effect or how long the effects last, it won’t change the toxicity of CBD.