Can CBD Oil Cause Tingling In Hands And Feet


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You have probably heard of the benefits surrounding CBD, but what are the potential side effects you ought to be aware of? Columnist Ezekiel Lim says there is key information needed for patients and caregivers considering CBD for peripheral neuropathy. How do you know when you're feeling your CBD? CBD is a powerful compound, but even with all its benefits, the effects you feel can be quite subtle. Sometimes you can take CBD without even realizing it's working. Why? Because you don't know what you're looking for. With most health and wellness products, there are side-

The Potential Side Effects of CBD

Wendy Rose Gould is a lifestyle reporter with over a decade of experience covering health and wellness topics.

Verywell Mind articles are reviewed by board-certified physicians and mental healthcare professionals. Medical Reviewers confirm the content is thorough and accurate, reflecting the latest evidence-based research. Content is reviewed before publication and upon substantial updates. Learn more.

Steven Gans, MD is board-certified in psychiatry and is an active supervisor, teacher, and mentor at Massachusetts General Hospital.

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Generally speaking, CBD is considered a safe substance when applied topically or taken orally. There are, however, some potential side effects to keep in mind when using this substance, the majority of which are mild.

Common Side Effects of CBD

The most comment side effects of CBD include drowsiness, gastrointestinal issues, dry mouth, reduced appetite, nausea, and interaction with other medications. Those are outlined in detail below.


Some common side effects when using CBD include drowsiness and sedation. This is also considered a benefit, but Dr. Jas Matharu-Daley, a physician and chief medical officer for a CBD brand, notes that the effects might be too strong if you’re also taking CBD with other sedating medications.

Gastrointestinal Issues

Some people may get diarrhea or liver problems [when using CBD]. This is dependent on the individual and their medical history, so monitoring is important,” says Dr. Matharu-Daley.

Dry Mouth

Also known as “cotton mouth,” CBD can potentially cause your mouth and eyes to feel very dry. Though this side effect is more likely to occur with THC, it can happen with CBD as well.

Can Interact With Other Medications

CBD might interfere with the other medications you take. Dr. Matharu-Daley says it’s important to talk to your doctor about whether CBD could affect your existing prescriptions.


In some cases, those who ingest CBD supplements might experience nausea, says Dr. Matharu-Daley. This depends on how sensitive the person is to CBD, as well as the amount they ingest.

Because CBD supplements come in so many different forms—such as oils, gummies, tinctures, and vapors—the amount that’s actually absorbed can vary drastically. This, combined with each person, will ultimately affect which (if any) CBD side effects you might experience.

What Is Cannabidiol (CBD)?

CBD—the abbreviation for cannabidiol, a substance that’s generally derived from the hemp plant—has skyrocketed in popularity over the last five years. In fact, according to research, “CBD” as a Google search term remained stable from 2004 to 2014 but has since ballooned by up to 605%.

CBD is one of the many chemical compounds that is found in the cannabis plant—referred to as cannabis sativa. There are two primary parts of the plant that humans use. One is THC, or Delta-9-Tetrahydrocannabinol, and the other is CBD. Though they’re from the same plant, THC and CBD are quite different from each other.

“CBD is not an intoxicating substance, whereas THC is a psychoactive that can get you high,” explains Dr. Jas Matharu-Daley, a physician and consultant for a brand that specializes in CBD production.

Are There Any Benefits Associated With Using CBD?

There are several reasons why someone might want to use CBD. The substance can be found in a multitude of products ranging from pain-relieving creams to edible tinctures to skincare. Research is still underway, but over the last few decades scientists have become more aware of how CBD might be beneficial when applied either topically or ingested.

“Since discovering the endocannabinoid system (ECS) in the body in the 1990s, CBD has been researched more extensively. The ECS is a central regulatory system restoring normal balance and homeostasis in a range of human physiologic systems throughout the body and brain and has cannabinoid receptors and chemicals in its function,” explains Dr. Matharu-Daley.

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CBD benefits include the following:

  • CBD can have positive impact on the brain. In fact, Dr. Matharu-Daley says that the substance is legally prescribed in a specific medication for certain severe forms of epilepsy in children.
  • It has also been shown to have anti-inflammatory properties, which is why you often see CBD in topical products such as oils, creams, and lotions.
  • Some research points to CBD’s ability to relieve stress and anxiety.
  • It has been used as a nausea treatment in some countries.
  • CBD may potentially reduce pain symptoms.
  • It has antioxidant properties, which means it can help fight off free radical damages that leads to premature aging.
  • Regarding skincare, CBD may help reduce excessive oil production in those with very oily skin types.

Ultimately, the primary reasons why people use CBD is because it tends to have calming, relaxing, pain-reducing effects. It has been used to alleviate joint pain and nerve pain, reduce anxiety and stress, treat insomnia, improve migraines, and address nausea.

CBD Is Still an Unregulated Substance

It’s important to point out that CBD is not regulated by the FDA and therefore dosages might not be accurate. It’s also difficult to know what an appropriate dose is the first time you try a new product.

“If the CBD is from a reputable source and one that has been inspected by a third-party independent lab, the content of CBD is more reliable,” notes Dr. Matharu-Daley. “The CBD should be organically grown, free of pesticides and heavy metals, and not sourced in food which can affect absorption. Generally, CBD is safe and side effects are few at low doses.”

A Word From Verywell

CBD is technically an unregulated substance in the United States and therefore it ought to be used with caution. This is especially important for those taking additional medications and/or those with ongoing medical issues. That said, preliminary research on CBD and its benefits are promising in relation to helping with mild to moderate health concerns and it is generally considered a safe substance. Health professionals do not consider CBD a cure-all for serious medical issues, including cancer.

As with any sort of supplement, we recommend speaking to your medical doctor about whether using CBD makes sense for you. Your doctor can also recommend certain products that align with your needs and help ensure you get the correct dosage.

What Patients Should Know About CBD for Peripheral Neuropathy

The pain associated with peripheral neuropathy symptoms makes everyday life difficult for patients. And the medication needed to treat the underlying physical symptoms of familial amyloid polyneuropathy can prove too costly for those on a limited budget.

Alternative methods for managing neuropathic pain are available. CBD is an emerging alternative treatment that allegedly has significant pain-reducing qualities.

What is CBD?

Cannabidiol (CBD) is one of the most abundant compounds in the marijuana plant. CBD products come primarily in the form of oils, topical ointments, and infused food items. However, with the exception of one prescription product to treat rare forms of epilepsy, the U.S. Food and Drug Administration has not approved any other CBD products.

Recent clinical research, including a study by researchers at Scotland’s University of Glasgow , looks at CBD’s effects on anxiety, movement, and pain. The study found that a “meaningful proportion” of patients exhibited improvements in sleep quality and pain when administered CBD.

Is CBD for real?

CBD’s impact could be a placebo effect, though the results of the study at the University of Glasgow appear to show otherwise. The emergence of clinical studies corroborating CBD’s pain-relieving qualities and a surge in CBD-based retail stores may offer peripheral neuropathy patients a solution for foot pain.

The plausibility of CBD being a reliable treatment may be subjective. Many peripheral neuropathy patients, including my mother-in-law, find THC products are a suitable method for alleviating neuropathic pain. THC’s alleged calming effects may benefit patients with chronic tingling and burning sensations of the feet, but these effects may not necessarily be true for everyone with peripheral neuropathy symptoms.

Not every patient with polyneuropathy will be quick to adapt to CBD as a solution for pain. My mother-in-law struggles with the side effects of gabapentin: drowsiness, dizziness, and fatigue. This has led her to use prescribed marijuana. Her medical marijuana use has helped alleviate the pain, burning, and tingling in her limbs.

Ultimately, CBD may provide temporary relief from pain with potentially fewer side effects than medicines such as gabapentin.

Note: FAP News Today is strictly a news and information website about the disease. It does not provide medical advice, diagnosis, or treatment. This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website. The opinions expressed in this column are not those of FAP News Today or its parent company, BioNews Services, and are intended to spark discussion about issues pertaining to familial amyloid polyneuropathy.

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About the Author

Ezekiel Lim Ezekiel is caregiver to his mother-in-law, who has familial amyloid polyneuropathy. He holds a bachelor’s degree in strategic and organizational communications from Temple University and currently lives in Philadelphia, Pennsylvania. When not writing, he’s skateboarding or hanging out with his wife, Maryann.


I have severe pain in both feet and trouble sleeping and Bella Rose CBD oil really helps in both cases. My pain is caused by Neuropathy. It gets so bad that it’s hard to do anything. This is the best product that I have found yet.

Im trying to find something for pain in my foot neuropathy. Its terrible. I cant sleep at night. All through the day all i can think about is my foot pain . The main pain is actually in my big to and toes. Please help

I hope more clinical trials are conducted to validate the pain alleviating properties of CBD products to treat peripheral neuropathy.

My wife bought me a “Sports gel”, main active ingredient is CBD. plus a touch of capsaicin and arnica. I’ve had ideopathic pedal neuropathy for several years and learned to live with it on my daily exercise walks. Nothing my primary care GP could find to help it.

A natural-born sceptic, science-rooted, I’ve been trying this out in disciplined fashion. Light application once a day for the first 5 days brought pretty amazing results. While general numbness didn’t vanish. Nothing like that. A great of sensitivity to ground impact, terrain, added experience returning to my walks.

Cut it back to every other day. Worked just as well. Now, a few more weeks have passed and I’ve gone as long as 4-day intervals with no application. and no diminishing of the positive effect.

I’m returning to every other day, starting tonight. wondering if the effect will become greater.

For the record, lost a bunch of weight a few years back. Now, weigh ~180#, 5’10”, decent physical shape for my age after a lifetime of one or another sport, outdoors physical activity, a lifetime walker [using top quality hiking or sports shoes the last 50 years. decent work shoes before that]. I’m 83.

5 Signs You’re Feeling Your CBD

How do you know when you’re feeling your CBD? CBD is a powerful compound, but even with all its benefits, the effects you feel can be quite subtle. Sometimes you can take CBD without even realizing it’s working. Why? Because you don’t know what you’re looking for. With most health and wellness products, there are side-effects that are obvious. CBD is non-intoxicating and has no side effects. And those are serious benefits. However, it can make it difficult for people to realize their CBD is working. Hemp extracts are rich in cannabidiol and contain less than 0.3% THC. Many people expect to feel an effect similar to the haziness brought on by marijuana, but because of its low THC content they never feel a sense of “high.” And that’s when they assume something is off. Again, it’s important to remember that the effects you feel from CBD are subtle. But when you know what to look for you can definitely tell when your CBD is working. Here are 5 things to tip you off.

1. A Calm Mind

We live in a busy world where things can get pretty stressful. There’s nothing worse than a cluttered brain unable to focus. When your mind is tense and bogged down with a million thoughts, it’s impossible to do work efficiently. Being able to calm your mind and focus is valuable. Suddenly the world seems like an easier place to be in, it’s easier to be productive, and stress is easier to handle. One of the ways you can tell your CBD is working is when you feel that fantastic calm wash over your mind. There’s something special about the way that CBD seems to relax the mind and allow you to deal with your everyday tasks without getting overwhelmed. People really appreciate having a way to regain their mental calm in the middle of a stressful day, and CBD can help you keep your cool. When you’re really feeling the effects of CBD, you’ll know it, because your mind will feel clear, calm, and function at its potential.

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2. Your Body Relaxes

CBD provides an array of desirable effects, and one of the things people love most about is how it relaxes the body. Day-to-day life can get tense. Maybe you’re stressed about a big meeting, or maybe you’ve got a huge project you’re working on and can’t seem to get a break. Stress often manifests itself in your body and can be a very real physical response to your mental state. When you’re sitting in traffic or pulling an all-nighter to finish a work project, your brain translates that mental stress into a physical reaction that can be harmful to your health. The hypothalamus is the part of your brain that dictates whether or not it’s time to distribute stress hormones throughout your body. The hormones your body produces when you’re stressed are the same hormones that trigger your body’s fight-or-flight response. Suddenly your heart and mind are racing and your muscles are prepped and ready for anything. While this response is important in survival situations, if you’re stressed like this day after day, it can have some seriously negative effects on the body. Fortunately, CBD is here to help. When you’re feeling your CBD, you’ll notice that your body is nice and relaxed. The stress of everyday life just doesn’t seem to have the same impact on your body that it normally does. With CBD you can enjoy a relaxed, stress-free feeling in your body. Your fight-or-flight mechanism is often triggered by stress, but it doesn’t have to be that way. The next time you take CBD, pay attention to that relaxed feeling in your body.

3. The Gentle Tingle in Your Skin

One of the most distinct ways to tell that you’re feeling your CBD is the gentle and highly enjoyable tingling feeling in your skin. This is particularly noticeable with CBD-infused topicals, but it’s often present with the use of oil tinctures and vape pens as well. People love the tingling feeling they experience when using CBD, and it’s one of the easiest ways to tell that you’re feeling your CBD. A gentle tingling feeling can be quite therapeutic and many people really appreciate the experience when they are suffering from muscle pain or soreness. Whether you’re using a CBD topical, edible, vape pen, or tincture, if your skin has a gentle tingling feeling afterward you’re feeling your CBD.

4. You Find Yourself Thinking More Clearly

A cluttered mind can be one of life’s most difficult challenges. We are frequently faced with harmless, but incredibly frustrating situations such as traffic jams, or an overload of stress from work. Though these situations don’t present a direct physical danger, the body can’t really tell the difference and reacts as if your mortality is at stake. This reaction is hugely important and gives us the strength we need when we’re in serious situations. Hormones help ignite your mind and make you more alert. However, this alertness is caused by stress that can lead to unclear thoughts and actions. The fact of the matter is that most of us don’t live in situations where we need our fight-or-flight mechanism all that often. One of the best feelings is to have the ability to think clearly. The effects of CBD can sometimes be less than obvious, but the clarity you feel in your thoughts is well-appreciated. This is one of the things people notice most frequently when they’re feeling the effects of CBD. It’s also one of the ways you can be certain your CBD is doing its job.

5. Feeling Sleepier Around Bedtime

When you take CBD, the most enjoyable feeling might be when it’s time to go to sleep. CBD provides a wealth of benefits, particularly the feeling before bedtime. It’s estimated that nearly 16 million adults in the U.K. suffer from insomnia. That’s roughly a third of the U.K’s adult population, which means this is a common issue. Fortunately, if you use CBD daily, you’ll notice a difference when it’s time to sleep. One of the most commonly reported effects of CBD is feeling sleepy when it’s time to go to bed. There’s almost no better feeling than laying down in bed and feeling perfectly tired and ready for sleep. People use CBD for a huge variety of reasons, and no matter why you’re using CBD, if you’re experiencing some or all of these 5 signs, you know you’re feeling the power of CBD at work!

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